Generated by All in One SEO v4.9.10, this is an llms.txt file, used by LLMs to index the site. # LumaCyte ## Sitemaps - [XML Sitemap](https://lumacyte.com/sitemap.xml): Contains all public & indexable URLs for this website. ## Posts - [Beyond Viability: Why Cell Vitality Matters in Living Therapies](https://lumacyte.com/biomanufacturing/beyond-viability-why-cell-vitality-matters-in-living-therapies/) - Knowing whether a cell is alive is no longer a sufficient quality measure in the manufacturing of cellular therapies. Traditional viability assays have long provided a fast and familiar way to determine whether cells meet a basic live or dead threshold, but those assays do not fully describe whether living cells are healthy, functional, resilient, - [From Method to Standard: What ISO 16921-2 Means for Viral Vector Measurement](https://lumacyte.com/biomanufacturing/from-method-to-standard-what-iso-16921-2-means-for-viral-vector-measurement/) - For years, viral vector manufacturing has advanced faster than the analytical frameworks used to measure it. While production platforms have scaled and diversified, the methods used to quantify viral vectors have remained fragmented, often varying across laboratories, organizations, and stages of development. This lack of alignment has created a persistent challenge: not just how to measure viral vectors, - [Real-Time Insight for Viral Vector and Vaccine Manufacturing](https://lumacyte.com/biomanufacturing/real-time-insight-for-viral-vector-and-vaccine-manufacturing/) - Viral vectors and vaccines play a central role in modern biomanufacturing, supporting applications that range from gene therapy to global immunization programs. These products are defined not only by their composition, but by their ability to infect target cells and drive a functional biological response. As demand grows, especially in situations that require rapid scale-up, - [From Cell Bank to Final Dose: Monitoring Quality Across the Therapy Lifecycle](https://lumacyte.com/biomanufacturing/from-cell-bank-to-final-dose-monitoring-quality-across-the-therapy-lifecycle/) - Cell and gene therapies undergo a complex manufacturing and regulatory journey before reaching patients for treatment. The path begins with cells from a patient, qualified healthy donor, or cell bank and ends with a final formulated dose ready for administration. Each stage along the path introduces potential variability, and regulators increasingly expect manufacturers to demonstrate - [From Cell Bank to Final Dose: Monitoring Quality Across the Therapy Lifecycle](https://lumacyte.com/biomanufacturing/from-cell-bank-to-final-dose-monitoring-quality-across-the-therapy-lifecycle/) - Cell and gene therapies undergo a complex manufacturing and regulatory journey before reaching patients for treatment. The path begins with cells from a patient, qualified healthy donor, or cell bank and ends with a final formulated dose ready for administration. Each stage along the path introduces potential variability, and regulators increasingly expect manufacturers to demonstrate - [From Data to Decisions: How Label-Free Analytics Support Regulatory Confidence in Cell Therapy](https://lumacyte.com/uncategorized/from-data-to-decisions-how-label-free-analytics-support-regulatory-confidence-in-cell-therapy/) - Expectations for regulatory compliance of cell and gene therapies must continue to adapt as therapies move from research to early clinical development to full-scale commercialization. Regulatory agencies like the FDA and EMA are calling for deeper process understanding, stronger comparability frameworks, and real-time evidence of control across the entire manufacturing lifecycle. This reflects a broader - [Real-Time Cellular PAT: The Key to Consistent, Scalable Biomanufacturing](https://lumacyte.com/uncategorized/real-time-cellular-pat-the-key-to-consistent-scalable-biomanufacturing/) - Cell and gene therapies are moving from R&D to the clinic at an unprecedented pace. As the industry scales, manufacturers are challenged with maintaining a consistent level of precision and control over processes involving living cells. Unfortunately, traditional quality control methods, such as those based on batch testing and endpoint assays, only offer snapshots into - [LumaCyte Wins 2025 Biotech Breakthrough Award for Predictive Analytics Solution of the Year](https://lumacyte.com/uncategorized/lumacyte-wins-2025-biotech-breakthrough-award-for-predictive-analytics-solution-of-the-year/) - LumaCyte has been named a 2025 BioTech Breakthrough Award winner, earning top honors in the category of Predictive Analytics Solution of the Year—a recognition that underscores the company’s leadership in nextgeneration biomanufacturing analytics. The annual BioTech Breakthrough Awards celebrate the most innovative companies, technologies, and products shaping the future of life sciences. At the heart of this achievement is Laser Force Cytology™ (LFC), LumaCyte’s groundbreaking, labelfree singlecell analytical platform. As a cellular - [Could Radiance Help Improve The Effectiveness of The Influenza Vaccine?](https://lumacyte.com/treatment/could-radiance-help-improve-the-effectiveness-of-the-influenza-vaccine/) - Posted by Colin Hebert, VP Biotechnology & Keya Rodrigues, Quality Assurance Bioengineer This year’s particularly bad flu season has scientists heavily focused on identifying better ways to produce the influenza vaccine. According to CDC data as of February 17,2018, there was widespread influenza activity across most of North America (1), and one of the contributing factors for - [Beyond Fluorescence: Why Traditional Cell Analytics Fall Short](https://lumacyte.com/uncategorized/beyond-fluorescence-why-traditional-cell-analytics-fall-short/) - Today’s cell-based therapies demand analytics that move as fast as the science itself, yet many laboratories still depend on tools built for a different era. Techniques like flow cytometry, ELISA, and qPCR have long been trusted for measuring critical quality attributes (CQAs) such as purity, potency, and viability. However, these traditional assays all share the - [Driving Innovation in Biomanufacturing: Real-Time Analytics, PAT, and Regulatory Guidance](https://lumacyte.com/biopharmaceutical/driving-innovation-in-biomanufacturing-real-time-analytics-pat-and-regulatory-guidance/) - Introduction Biomanufacturing, especially in the field of cell and gene therapies (CGTs) and vaccines, is undergoing rapid transformation. As the demand for these life-saving treatments grows, so does the need for efficient, consistent, and high-quality production. In this blog post, we explore key areas driving innovation in biomanufacturing, including real-time precision analytics, Process Analytical Technology - [Faster Viral Detection For Vaccine Development](https://lumacyte.com/viral/faster-viral-detection-for-vaccine-development/) - Could we finally have a faster, more objective analytical tool to rapidly measure viral infectivity for vaccine development and production? Scientists and bioengineers at Thermo Fisher Scientific and LumaCyte believe we do. This peer reviewed work will be published on September 12th in the prestigious journal, Vaccine, by Elsevier, detailing how LumaCyte’s Radiance™ instrument, based on Laser - [The Role of Laser Force Cytology™ In Continuous Biopharmaceutical Manufacturing](https://lumacyte.com/biopharmaceutical/the-role-of-laser-force-cytology-in-continuous-biopharmaceutical-manufacturing/) - Posted by Colin Hebert, VP Biotechnology & Keya Rodrigues, Quality Assurance Bioengineer Continuous processing has been utilized at scale in the chemical industry for decades due to its increased production efficiencies, reduced capital costs, and improved product quality. However, its adoption by the biopharmaceutical industry for the production of cell-based products such as monoclonal antibodies and vaccines - [The Ab Dilemma: What Have We Learned and Where Are We Going?](https://lumacyte.com/data/the-ab-dilemma-what-have-we-learned-and-where-are-we-going/) - Margaret E. McCoy, PhD, JD, Executive Director, Assay Development and Regulatory Affairs & Keya Rodrigues, M S, Quality Assurance Bioengineer Let’s go back to the basics for a moment and talk about antibodies (Abs). Active and passive Ab immunization has saved millions of lives over the years with therapies that, respectively, induce our own immune system - [Beyond Flow Cytometry: How Laser Force Cytology™ is Transforming Cellular Analytics ](https://lumacyte.com/uncategorized/beyond-flow-cytometry-how-laser-force-cytology-is-transforming-cellular-analytics/) - For decades, flow cytometry has provided valuable insights about single cell populations, but as biomanufacturing and cell therapy advances, precision, efficiency, and speed of analytics have become more critical than ever. Often labeled methods come with limitations that can limit process knowledge — antibody selection bias, complex staining protocols, reagent variability, and time-consuming data - [Phacilitate Advanced Therapies Week and CASSS Well Characterized Bioprocess (WCBP) 2025: Driving Towards a Future of Advanced Precision Analytics in Biologics and ATMP Manufacturing](https://lumacyte.com/uncategorized/phacilitate-advanced-therapies-week-and-casss-well-characterized-bioprocess-wcbp-2025-driving-towards-a-future-of-advanced-precision-analytics-in-biologics-and-atmp-manufacturing/) - The Phacilitate Advanced Therapies Week, January 20-23, 2025, in Dallas, Texas, and CASSS Well Characterized Bioprocess (WCBP), January 28-30, 2025, in Washington, DC once again proved to be two pivotal events focused on the future of advanced bioprocess and manufacturing. Each conference brought together global experts, industry thought leaders, and solution and service innovators to Phacilitate Advanced Therapies Week and CASSS WCBP 2025 spotlight precision cellular PAT analytics in bioprocess and ATMP manufacturing, driving advancements in cell and gene therapies. - [Reflecting on ISCT 2024: The Time is Right for PATs and Advanced Analytics](https://lumacyte.com/biopharmaceutical/reflecting-on-isct-2024-the-time-is-right-for-pats-and-advanced-analytics/) - Our team had an amazing time at ISCT 2024 in Vancouver, Canada! The event was filled with inspiring talks focused on advancing cell therapy development and how to scale the manufacturing of these lifesaving therapies. Engaging with experts from across the globe on how we together can breakthrough sector challenges and collaborate to drive novel - [Why Measurement of Viral Infectivity Matters and How To Improve It](https://lumacyte.com/biopharmaceutical/why-measurement-of-viral-infectivity-matters-and-how-to-improve-it/) - Posted by Colin Hebert, VP Biotechnology & Keya Rodrigues, Quality Assurance Bioengineer Viral quantification involves the counting of viruses or viral molecules in a known volume to determine their concentration. It plays an essential role in studies carried out in the fields of recombinant protein production, viral vaccine production and infectious disease. Methods used in viral quantification - [Population Dynamics: CHO Cells Revisited](https://lumacyte.com/data/population-dynamics-cho-cells-revisited/) - Posted Keya Rodrigues, MS, Quality Assurance Bioengineer & Margaret McCoy, PhD, JD, Executive Director, Assay Development and Regulatory Affairs Chinese Hamster Ovary (CHO) cells and other mammalian cells are commonly used as a cell culture line for biomanufacturing proteins of interest. When put under osmotic stress, these cells often display higher specific productivity (1) (2). Interestingly, with - [Macrophages: The First Responder](https://lumacyte.com/product/macrophages-the-first-responder/) - Keya Rodrigues, MS, Quality Assurance Bioengineer One of the first responders at any infection or injury site in a host are macrophages. A type of white blood cell, macrophages contribute to the innate immune system by rapidly fighting infections in a non-specific way and “teach” the adaptive immune system to react in a very - [Spring Back To Isbiotech 2018, Norfolk, VA](https://lumacyte.com/event/spring-back-to-isbiotech-2018-norfolk-va/) - Posted by Colin Hebert, VP Biotechnology & Carolyn Maki, VP, Business Development and Partnerships Earlier this month, two members of the LumaCyte team attended and presented at the 8th annual ISBiotech Spring meeting. Although there was a change of venue from Washington D.C. to Norfolk, VA, this year the quality of both the scientific presentations and interactions - [Peter's Perspective: Radiance Gives Real Time Results With Incredible Ease](https://lumacyte.com/product/peters-perspective-radiance-gives-real-time-results-with-incredible-ease/) - By Peter Hayes, PhD student at Carnegie Mellon University (CMU) I recently had the opportunity to visit LumaCyte at their corporate headquarters in Charlottesville. With little knowledge of Radiance prior to my visit, I was surprised how quickly I became an experienced user capable of running samples and analyzing data. While the Laser Force Cytology and microfluidic design of Radiance - [The Power Of Multivariate Data Analysis In Uncovering The Nuances In Complex Data Sets](https://lumacyte.com/data/the-power-of-multivariate-data-analysis-in-uncovering-the-nuances-in-complex-data-sets/) - Laser Force Cytology, the cutting-edge single cell, label-free technology powering LumaCyte’s Radiance instrument, has applications spanning viral infectivity, neutralization assays, immunotherapy (CAR T, TCR), anti-viral development, phenotypic drug studies, and stem cell studies. LumaCyte’s Radiance instrument, employs proprietary artificial cells for calibration that more closely mimic the properties and behavior of cells than do the - [Viral Infection Monitors For Combined Enhanced Oncological Treatments](https://lumacyte.com/treatment/viral-infection-monitors-for-combined-enhanced-oncological-treatments/) - Posted by Delphine Le Roux, PhD, Technical Sales Executive LumaCyte’s Radiance instrument has recently been featured in a highly anticipated melanoma cancer treatment discovery paper in Science Translational Medicine (1) where it was used to confirm and augment conventional methods of analysis. The paper highlights the combination of three oncology therapeutic options and its benefit ## Pages - [Home](https://lumacyte.com/) - Real‑time bioprocess analytics and predictive cell phenotyping with LumaCyte’s label‑free single‑cell insights to improve ATMP and biologics production consistency and quality. - [Schedule a Meeting - ISSCR 2026](https://lumacyte.com/isscr-2026/) - Schedule a Meeting Schedule a Meeting with the LumaCyte Team Thank you so much for your interest in LumaCyte. Please select a date and time that works with your schedule, our team looks forward to meeting you. Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to complete this - [Measurement of Infectious Titers and Total Viral Particle Counts to Fully Characterize Your Viral Process and Product](https://lumacyte.com/resources/tech-notes/measurement-of-infectious-titers-and-total-viral-particle-counts-to-fully-characterize-your-viral-process-and-product/) - Measurement of Infectious Titers and Total Viral Particle Counts to Fully Characterize Your Viral Process and Product In this technical note, we demonstrate the impacts of various process insults, namely elevated temperature, low pH, and freeze-thaw cycles on the virulence of viral particles and the capability of Radiance® to assess these changes quickly. The Malvern - [Radiance® Label-Free T-cell Activation Monitoring](https://lumacyte.com/resources/tech-notes/radiance-label-free-t-cell-activation-monitoring/) - Radiance® Label-Free T-Cell Activation Monitoring Here we present LFC™ as a technology that enables a rapid and sensitive method of monitoring T-cell activation using a combination of optical pressure and microfluidics to measure intrinsic biophysical and biochemical changes in cells. Please request the Tech Note using the form below. Please enable JavaScript in your browser - [Laser Force Cytology™ (LFC™) Monitoring of Influenza Virus Infection](https://lumacyte.com/resources/tech-notes/laser-force-cytology-lfc-monitoring-of-influenza-virus-infection/) - Laser Force Cytology™ Monitoring of Influenza Virus Infection In this technical note, we present the utility for using LFC™ as a rapid, quantitative method to assess viral infectivity for use in real-time bioreactor monitoring and other applications including neutralization assays. Please request the Tech Note using the form below. Please enable JavaScript in your browser - [Zika virus neutralization using Laser Force Cytology™ (LFC™)](https://lumacyte.com/resources/tech-notes/zika-virus-neutralization-using-laser-force-cytology-lfc/) - Zika Virus Neutralization Using Laser Force Cytology™ In this technical note, we present the application of LFC™ and Radiance® to directly assess the neutralization potential of antibodies against specific viruses (Zika virus in particular), offering invaluable insights into the development and testing of vaccines and therapies. Please request the Tech Note using the form below - [Radiance® Rapid Label-Free Monitoring of Coronavirus Infectivity](https://lumacyte.com/resources/tech-notes/radiance-rapid-label-free-monitoring-of-coronavirus-infectivity/) - Radiance® Rapid Label-Free Monitoring of Coronavirus Infectivity In this technical note, we present LFC™ as a technology that increases the speed and precision of viral titer measurements, enabling compression of important R&D efforts and the improvement of scale-up and production timelines, as well as formulations, release assays, and viral safety testing timelines. Please request the - [Radiance® Label-Free Monitoring of AAV Transfection in HEK293 Cells Using Laser Force Cytology™ (LFC™)](https://lumacyte.com/resources/tech-notes/radiance-label-free-monitoring-of-aav-transfection-in-hek293-cells-using-laser-force-cytology-lfc/) - Radiance® Label-Free Monitoring of AAV Transfection in HEK293 Cells Using Laser Force Cytology™ (LFC™) In this technical note, collaborative efforts are described between Catalent and LumaCyte to compare AAV production with three different transfection reagents using both LFC™ and a digital droplet PCR (ddPCR) based viral genome titer assay. A strong correlation was generated between - [Radiance® Rapid Viral Quantification of Adenovirus Infection of HEK293 Cells with Label-Free Laser Force Cytology™](https://lumacyte.com/resources/tech-notes/radiance-label-free-monitoring-of-adenovirus-infection-of-hek293-cells/) - Radiance® Rapid Viral Quantification of Adenovirus Infection of HEK293 Cells with Label-Free Laser Force Cytology™ In this technical note, we present the application of LFC and Radiance® to rapidly quantify adenovirus infection by correlating significant shifts in multiple optical force metrics with titer within 2 days post infection, ultimately aiding the ability to measure unknown - [Real-time Infectivity Monitoring for Measles Vaccine Production](https://lumacyte.com/resources/tech-notes/real-time-infectivity-monitoring-for-measles-vaccine-production/) - Real-time Infectivity Monitoring for Measles Vaccine Production In this technical note, we present the application of LFC™ as a valuable process analytical technology (PAT) to measure potency of live virus vaccines (LVVs) in upstream biomanufacturing processes with the goal of improving the speed, efficiency and quality of vaccine development and manufacturing. Please request the Tech - [AAV2 Transduction Analytics with Laser Force Cytology™](https://lumacyte.com/resources/tech-notes/aav2-transduction-analytics-with-laser-force-cytology/) - AAV2 Transduction Analytics Using Laser Force Cytology™ In this technical note, learn how LumaCyte’s Radiance® instrument and Laser Force Cytology™ technology allows for the precise and accurate measurement of AAV transduced cells without relying on a helper virus. Now developers and manufacturers alike can accelerate the production of life saving gene therapy products and improve - [MSC Differentiation Using Laser Force Cytology™](https://lumacyte.com/resources/tech-notes/msc-differentiation-using-laser-force-cytology-gated/) - Real-Time Monitoring of Mesenchymal Stem Cell (MSC) Differentiation Using Label-Free Laser Force Cytology™ In this technical note, learn how Laser Force Cytology™ offers a sensitive, label-free method for assessing and quantifying stem cell differentiation—ensuring rapid, precise measurements without the limitations of traditional methods. This tool will help you unlock the potential for enhanced R&D, process - [Leadership](https://lumacyte.com/leadership/) - Board of Directors & Scientific Advisors At LumaCyte, we are guided by a team of visionary leaders and distinguished experts dedicated to driving innovation and accelerating the delivery of life-saving therapies. This diverse group brings extensive experience, providing strategic guidance and scientific insight to ensure the highest standards of excellence and integrity in all that - [News Room](https://lumacyte.com/press-media/news-room/) - News & Events 2026 June 2 LumaCyte has been newly recognized in a global ISO viability standard, marking one of the most significant updates to cell viability assessment in decades. The standard incorporates LumaCyte’s label‑free optical and fluidic force approach, enabling earlier detection of functional decline and more consistent, reliable analytics for biologics and cell - [Press Releases](https://lumacyte.com/press-media/press-releases/) - Press Releases Latest Second Global ISO Standard Expands LumaCyte Measurement Framework to Mammalian Cell Viability June 2026 LumaCyte has been newly recognized in a global ISO viability standard, marking one of the most significant updates to cell viability assessment in decades. The standard incorporates LumaCyte’s label‑free optical and fluidic force approach, enabling earlier detection of - [Radiance](https://lumacyte.com/products/radiance/) - Explore Radiance®, LumaCyte’s next-gen cell analysis instrument delivering real-time, label-free single cell analytics. Enhance process control with cutting-edge PAT for cell therapy, vaccines, and biomanufacturing applications. - [Schedule a Meeting - CASSS 2026](https://lumacyte.com/schedule-a-meeting-casss-2026/) - Schedule a Meeting Schedule a Meeting with the LumaCyte Team We invite you to schedule a meeting with our LumaCyte team. Please select what you are most interested in discussing, a date and time that works with your schedule. Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to - [Scientist Course-Start the course](https://lumacyte.com/academy/scientist-course-start-the-course/) - Scientist Course - Start The Course - [Introduction](https://lumacyte.com/academy/introduction/) - Introduction Course - Start The Course - [Interviews](https://lumacyte.com/resources/interviews/) - Interviews & Panel Discussions Compressing the Gap: Where Patient Experience Meets Development Outcomes 1:13:24 Play Video Driving consistency, Yield, and Potency in Advanced Therapies with Predictive Analytics 14:10 Play Video Interview with LumaCyte's President & CBO, Renee Hart, Discussing Analytics, Regulatory and Bringing New Science to Market 15:37 Play Video Analytical Strategies for Next-Gen Biologics—Aligning - [Vaccines](https://lumacyte.com/applications/vaccines/) - Enhance vaccine development with LumaCyte’s label-free single-cell analysis. Accurately measure viral titers, TCID50, and perform infectivity and plaque assays to optimize production, dosing, and quality control. - [Biomanufacturing and PAT Analytics](https://lumacyte.com/applications/biomanufacturing-and-pat-analytics/) - LumaCyte’s Radiance® delivers label-free single-cell analysis for biomanufacturing. Monitor bioprocesses, stem cell differentiation, and cell bank characterization with real-time precision and PAT insights. - [Gene Therapy](https://lumacyte.com/applications/gene-therapy/) - Streamline gene therapy development with real-time, label-free single-cell analysis. LumaCyte’s Radiance® delivers insights for AAV transfection, triple transfection, and advanced gene therapy process analytics. - [Cell Therapy](https://lumacyte.com/applications/cell-therapy/) - Advance your cell therapy pipeline with LumaCyte’s label-free single-cell analysis. Measure predictive cell viability, monitor expansion, and assess activation and potency—all with real-time precision. - [Cell Vitality & Viability](https://lumacyte.com/applications/cell-viability-and-vitality/) - Discover how Radiance® by LumaCyte delivers label‑free, single‑cell vitality and viability analytics to predict cell performance and strengthen advanced biologics and ATMP workflows. - [Viral Vector Production Analytics](https://lumacyte.com/applications/viral-vector-production/) - Radiance delivers precise, real‑time viral vector analytics to optimize potency, boost yields, and strengthen safety across development and manufacturing. - [Applications](https://lumacyte.com/applications/) - Discover LumaCyte’s real-time, label-free technology for cell based assays, biological assays, and lab workflows. Enhance vaccine, gene, and cell therapy development with advanced single-cell analysis tools and proliferation insights. - [Technology](https://lumacyte.com/single-cell-analysis-technology/) - Discover label‑free single‑cell analysis and multivariate cellular PAT analytics with Laser Force Cytology™, enabling real‑time cellular insights and predictive process control. - [Predictive Machine Learning Multivariate Analysis](https://lumacyte.com/single-cell-analysis-technology/predictive-machine-learning-analytics/) - Discover how LumaCyte’s Radiance® applies machine learning (ML/AI) predictive analytics and single‑cell multivariate analysis to transform cellular data into early, actionable biological insight—advancing bioprocess development, manufacturing efficiency, and QC strategies - [Academy](https://lumacyte.com/academy/) - Get Access to LumaCyte's LFC™ Training Academy Welcome to the LumaCyte LFC™ Training Academy, where comprehensive training courses are designed to elevate your understanding of the Radiance® instrument and its revolutionary underpinning technology, Laser Force Cytology™. Immerse yourself in a transformative learning experience that explores our state-of-the-art instrument, empowering you to unlock the full potential - [Laboratory & Biostatistical Predictive Modeling Services](https://lumacyte.com/products/biostatistical-modeling-laboratory-analytics/) - Access high‑resolution, label‑free cellular analytics and predictive modeling through LumaCyte’s laboratory and biostatistical services. Accelerate development, reduce variability, and strengthen ATMP manufacturing with Radiance®‑powered insight. - [In Process Monitoring](https://lumacyte.com/applications/biomanufacturing-and-pat-analytics/in-process-monitoring/) - In‑Process Monitoring for Advanced Biomanufacturing The Challenge: Rapidly Shifting Bioprocesses Outpace Traditional Analytics and Monitoring Biomanufacturing relies on living systems, and living systems can change fast. Cell health, productivity, and functional performance shift in response to stress, infection or transfection events, media changes, or subtle upstream variation. Yet most in‑process monitoring tools rely on slow, - [Schedule a Meeting - ACS BIOT 2026](https://lumacyte.com/schedule-a-meeting-acs-biot-2026/) - Schedule a Meeting Schedule a Meeting with the LumaCyte Team We invite you to schedule a meeting with our LumaCyte team. Please select what you are most interested in discussing, a date and time that works with your schedule. Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to - [Tech Notes](https://lumacyte.com/resources/tech-notes/) - Technical Notes Real-Time Monitoring of Mesenchymal Stem Cell (MSC) Differentiation Using Label-Free Laser Force Cytology™ LumaCyte’s Radiance® instrument and Laser Force Cytology™ technology allows for the precise and accurate measurement of AAV transduced cells without relying on helper viruses or specific cell lines, accelerating the production of life saving gene therapy products and improving the - [Optimizing Bioprocess Parameters and Rapid Viral Infectivity Quantification with Laser Force Cytology™](https://lumacyte.com/resources/tech-notes/optimizing-bioprocess-parameters-and-rapid-viral-infectivity-quantification-with-laser-force-cytology_lp/) - Optimizing Bioprocess Parameters and Rapid Viral Infectivity Quantification with Laser Force Cytology™ The development of advanced therapies and viral vaccines increasingly demands analytical tools that can deliver rapid, precise, and scalable insights into cell health and viral infectivity. Traditional assays often slow, labor‑intensive, and dependent on labels or antibodies struggle to keep pace with modern - [Optimizing Bioprocess Parameters and Rapid Viral Infectivity Quantification with Laser Force Cytology™](https://lumacyte.com/resources/tech-notes/optimizing-bioprocess-parameters-and-rapid-viral-infectivity-quantification-with-laser-force-cytology/) - Optimizing Bioprocess Parameters and Rapid Viral Infectivity Quantification with Laser Force Cytology™Download The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [Cell Bank Characterization](https://lumacyte.com/applications/biomanufacturing-and-pat-analytics/cell-bank-characterization/) - Improve cell bank quality and starting material qualification with LumaCyte’s Radiance®. Discover label‑free analytics that deliver predictive cellular insights into health, vitality, and downstream functional performance for ATMP workflows. - [ReportR](https://lumacyte.com/solutions/reportr/) - LumaCyte’s ReportR™ is a revolutionary cell analysis software that streamlines data analysis with automated cloud-based reporting and enhanced real-time insights into complex biomanufacturing workflows. - [Meet Us at Advanced Therapies Week 2026](https://lumacyte.com/meet-us-at-advanced-therapies-week-2026/) - Meet Us at Advanced Therapies Week 2026 Sign Up Today! Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to complete this form.Name *FirstLastCompany Email *Company or Institution *Telephone Number *Connect with the LumaCyte Team - Please select a conference *Advanced Therapies Week 2026 - February 9-12, in San - [Oncolytic Virus Analytics](https://lumacyte.com/applications/vaccines/oncolytic_virus_analytics/) - Optimize oncolytic virus development with real‑time, helper‑free analytics. Radiance® captures phenotypic changes instantly to support product development, potency, and manufacturing quality. - [AAV Transduction](https://lumacyte.com/applications/gene-therapy/aav-transduction/) - Accelerate AAV transduction with real‑time, label-free analytics, no helper virus required. Radiance® delivers precise, rapid insights to improve yields and potency. - [Potency Assays](https://lumacyte.com/applications/vaccines/potency-assays/) - LumaCyte’s Radiance® delivers real-time viral potency assays for vaccine manufacturing, replacing slow plaque and TCID50 methods. Rapid, label-free infectivity and viral titer analysis, from predictive cell bank qualification to ensuring precise potency with optimal yields. - [AAV Transfection](https://lumacyte.com/applications/gene-therapy/aav-transfection/) - Optimize AAV transfection with Radiance® Laser Force Cytology™—from cell bank qualification to predictive downstream projection success with real-time, label-free monitoring. - [Stem Cells](https://lumacyte.com/applications/cell-therapy/stem-cells/) - Radiance® Laser Force Cytology™ enables rapid, label-free stem cell analysis for in-process monitoring, cell bank qualification, and predictive stem cell function post-thaw. Contact experts at LumaCyte today. - [Publications](https://lumacyte.com/resources/read-the-publications/) - Publications Are Real-time Gene Therapy Results Possible? Published by Fierce Biotech, 2021 Read More Rapid In-Process Measurement of Live Virus Vaccine Potency Using Laser Force Cytology: Paving the Way for Rapid Vaccine Development Vaccines, 2022 Reilly McCracken, Noor Al-Nazal, Travis Whitmer, Sijia Yi, James M. Wagner, Colin G. Hebert, Matthew J. Lowry, Peter R. Hayes, - [Are Real-Time Gene Therapy Results Possible?](https://lumacyte.com/resources/read-the-publications/are-real-time-gene-therapy-results-possible/) - Are Real-time Gene Therapy Results Possible? As science and technology companies continue to make advancements in vaccine and viral vector-based gene therapy development, there is an increasing need for analytical techniques that can help assess quality parameters, especially in real-time. In a step toward increasing the speed of process development and improvement, Catalent collaborated with - [Neutralization Assays](https://lumacyte.com/applications/vaccines/neutralization-assays/) - Optimize virology assays and plaque reduction neutralization tests with label-free, cell-based solutions using Laser Force Cytology technology. Revolutionize neutralization testing in vaccine development with real-time analytics and monitoring. - [Contact Sales](https://lumacyte.com/contact-sales/) - Contact Us Today Speak With a Sales Team Member Would you like to learn more about LumaCyte’s transformative Laser Force Cytology™ technology? Just fill out the form below and one of our sales representatives will get back to you. Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to - [2019 Global Single-Cell Analysis New Product Innovation Award for Its Novel Laser Force Cytology Technology.](https://lumacyte.com/resources/read-the-publications/2019-global-single-cell-analysis-new-product-innovation-award-for-its-novel-laser-force-cytology-technology/) - 2019 Global Single-Cell Analysis New Product Innovation Award for Its Novel Laser Force Cytology Technology Based on its recent analysis of the global single-cell analysis market, Frost & Sullivan recognizes LumaCyte, LLC (LumaCyte) with the 2019 Global New Product Innovation Award for its groundbreaking Laser Force Cytology™ (LFC™) technology. 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Please enable JavaScript in - [Sitemap](https://lumacyte.com/sitemap/) - Sitemap LumaCyte's Laser Force Cytology™ for Advanced Manufacturing Cell Based & Biological Assay Applications Real-Time Bioprocess & Cell Bank Monitoring for Biomanufacturing In Process Monitoring Cell Bank Characterization Process Optimization & Scale Up Label-Free Viral Infectivity Assays for Vaccine Innovation Real-Time Analytics for Oncolytic Virus Production and Development Advanced Neutralization Assays: Fast, Label-Free Virology Testing - [Limited-Time Radiance Price Lock Opportunity](https://lumacyte.com/limited-time-radiance-price-lock-opportunity/) - Limited-Time Radiance Price Lock Opportunity How will you harness the power of Laser Force Cytology™ to accelerate the development and production of life saving therapies faster than ever before? Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to complete this form.Name *FirstLastCompany Email *Company or Institution *Telephone Number - [Request a Quote](https://lumacyte.com/request-a-quote/) - Request a Quote Experience LumaCyte’s cutting edge technology firsthand and discover how our solutions can drive your research forward. Request a Quote How will you harness the power of Laser Force Cytology™ to accelerate the development and production of life saving therapies faster than ever before? Please enable JavaScript in your browser to complete this - [TheCyte Blog](https://lumacyte.com/the-cyte-blog/) - Explore LumaCyte’s blog for the latest insights on single-cell analysis, cellular analytics, biopharma advancements, and solutions for cutting-edge research. - [CAR-T](https://lumacyte.com/applications/cell-therapy/car-t/) - Discover label-free CAR T cell analysis and predictive donor cell analytics with Laser Force Cytology™ from LumaCyte. Designed for T-cell activation monitoring, non-invasive cell characterization, and fast potency results. Contact LumaCyte today. - [CPHI Frankfurt 2025](https://lumacyte.com/cphi-frankfurt-2025/) - CPHI Frankfurt 2025 Secure Your Spot to Meet Christof Hasse at CPHI Frankfurt 2025 Christof will be attending CPHI Frankfurt 2025 from October 28–30, and we’d love to connect with you in person. Whether you’re interested in strategic collaboration, CDMO partnerships, or learning more about LumaCyte’s transformative Laser Force Cytology™ technology, this is your opportunity - [2026 Radiance® Planning Survey](https://lumacyte.com/2026-radiance-planning-survey/) - 2026 Radiance® Planning Survey Help Us Plan Ahead, So We Can Deliver Even Better For You in 2026 As we prepare for an exciting 2026, your input is essential. The demand for Radiance® continues to grow, and we’re committed to scaling production, accelerating delivery timelines, and ensuring you have what you need, when you need - [Solutions](https://lumacyte.com/solutions/) - Optimize workflows with LumaCyte’s cell analysis solutions. Advanced tools for single-cell analysis deliver real-time insights and improved productivity. - [Services](https://lumacyte.com/services/) - Optimize your workflow with custom bioprocess services and advanced bioassay testing. LumaCyte provides tailored, cutting-edge solutions for your needs. - [Products](https://lumacyte.com/products/) - Transform your research with label-free single cell analysis tools. Get real-time insights with LumaCyte’s advanced systems for precision cell analysis. - [LumaCyte CAR T Donor & Patient Screening Service](https://lumacyte.com/applications/lumacyte-car-t-donor-patient-screening-service/) - Streamline CAR-T manufacturing with LumaCyte's donor and patient screening services. Predict manufacturing success and reduce failures with precision analysis. - [Illuminate](https://lumacyte.com/products/radiance/illuminate/) - Illuminate™ by LumaCyte enhances cell imaging and single-cell analysis with robust visualization, cellular image analysis, and data reporting tools—powering precision in bioprocessing and therapeutic development. - [Contact Us](https://lumacyte.com/contact-us/) - Contact Us Speak To One Of Our Experts Would you like to learn more about LumaCyte’s transformative Laser Force Cytology™ technology? You can email info@lumacyte.com or call (888) 472-9295. Alternatively, please fill out the form below and one of our technical experts will get back to you. Please enable JavaScript in your browser to complete - [Corporate](https://lumacyte.com/corporate/) - About LumaCyte Innovate. Discover. Transform.™ Accelerating the development and production of life-saving therapies through label-free, single-cell analysis. Accurate & Precise Viral Infectivity Analytics Real-time Bioprocess Monitoring Quantitative Data Without Subjectivity AAV Transfection & Transduction Monitoring Label-Free iPSC Differentiation Monitoring Flexible Platform Independent of Cell or Virus Our Mission LumaCyte’s mission is to provide developers and - [Laser Force Cytology™ Earns Inclusion in Certificate of Analysis](https://lumacyte.com/resources/tech-notes/laser-force-cytology-earns-inclusion-in-certificate-of-analysis/) - LumaCyte’s Laser Force Cytology™ Earns Inclusion in Certificate of Analysis (CoA), Elevating Precision in Viral Infectivity Measurement June 3rd, 2025 LumaCyte, a leader in advanced cellular analytics, announces that its transformative Laser Force Cytology™ (LFC™) technology has been included in its first Certificate of Analysis (CoA) for viral infectivity measurement. This milestone underscores the growing - [Careers](https://lumacyte.com/careers/) - Your Journey Starts Here Transform The Status Quo LumaCyte is always looking for potential new team members to help the company fulfill our mission. Do you have the passion and drive to help LumaCyte harness its innovative technology and accelerate the development, production, and delivery of life saving therapies and cures? How We Work Our - [Optimizing Cell Viability in Continuous and Batch Bioprocessing through Real-time Monitoring with Laser Force Cytology™](https://lumacyte.com/resources/tech-notes/optimizing-cell-viability-in-continuous-and-batch-bioprocessing-through-real-time-monitoring-with-laser-force-cytology-lp/) - Optimizing Cell Viability in Continuous and Batch Bioprocessing through Real-time Monitoring with Laser Force Cytology™ Discover how Laser Force Cytology™ (LFC) is redefining cell health monitoring in biomanufacturing. This technote delves into groundbreaking research using LumaCyte’s Radiance® instrument to evaluate the impact of oxidative stress on Vero cells. Unlike traditional assays, LFC offers real-time, label-free - [Optimizing Cell Viability in Continuous and Batch Bioprocessing through Real-time Monitoring with Laser Force Cytology™](https://lumacyte.com/resources/tech-notes/optimizing-cell-viability-in-continuous-and-batch-bioprocessing-through-real-time-monitoring-with-laser-force-cytology/) - Optimizing Cell Viability in Continuous and Batch Bioprocessing through Real-time Monitoring with Laser Force Cytology™Download The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [Customer Experience Survey](https://lumacyte.com/customer-experience-survey/) - Customer Experience Survey Help us continue to take innovation to the next level. Your experience and feedback are invaluable to us! Please provide your email for your free Amazon $20 gift card for completing this survey. Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to complete this form.Name - [Resources](https://lumacyte.com/resources/) - Resources LumaCyte's Library Dive into LumaCyte’s comprehensive library of scientific publications, technical notes, and posters showcasing our impact on life science bioprocess analytics and biomanufacturing. Publications Browse our collection of publications showcasing LumaCyte’s contributions to biopharmaceutical development and manufacturing. Tech Notes Discover in-depth technical insights on LumaCyte’s innovative tools and methodologies transforming the life sciences - [Schedule a Meeting with a Lumacyte Expert](https://lumacyte.com/schedule-a-meeting-with-a-lumacyte-expert/) - Schedule a Meeting Speak To One Of Our Experts Would you like to learn more about LumaCyte’s transformative Laser Force Cytology™ technology? Just fill out the form below and one of our technical experts will get back to you. Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to - [Process Optimization & Scale Up](https://lumacyte.com/applications/biomanufacturing-and-pat-analytics/process-optimization-scale-up/) - Process Optimization & Scale Up Laser Force Cytology™ Guides Process Optimization and Bioproduction Outcomes Process optimization and scale-up considerations serve as linchpins for the successful and efficient production of biopharmaceuticals. Optimization entails fine-tuning various parameters, such as cell culture conditions, media formulations, and purification processes, to enhance productivity and yield while maintaining product quality. Simultaneously, - [Press & Media](https://lumacyte.com/press-media/) - Press & News Current LumaCyte News, Publications and Press Releases Stay informed on LumaCyte’s latest advancements, news coverage, and industry recognition shaping the world of advanced biopharmaceutical bioprocess and manufacturing. For media inquiries, please contact us. Newsroom Stay up to date on LumaCyte’s latest news and advancements. Publications Laser Force Cytology™ publications introducing novel application - [Posters](https://lumacyte.com/resources/posters/) - Posters Oncolytic Virus PosterView Poster Vesicular Stomatitus Virus QuantificationView Poster - [Fluids & Accessories](https://lumacyte.com/fluids-accessories-confirmation/) - Fluids & Accessories Fluids & Accessories Thank you for contacting LumaCyte about fluids and accessories. Download the LumaCyte Safety Data Sheet. Thanks for contacting us! We will be in touch with you shortly. - [Measurement of Infectious Titers and Total Viral Particle Counts to Fully Characterize Your Viral Process and Product](https://lumacyte.com/resources/tech-notes/measurement-of-infectious-titers-and-total-viral-particle-counts-to-fully-characterize-your-viral-process-and-product-full-technote/) - Measurement of Infectious Titers and Total Viral Particle Counts to Fully Characterize Your Viral Process and ProductDownload The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [TCID50 vs Radiance Infectious Titer](https://lumacyte.com/tcid50-vs-radiance-infectious-titer/) - TCID50 vs Radiance Infectious Titer - [Radiance® Label-Free T-Cell Activation Monitoring](https://lumacyte.com/resources/tech-notes/radiance-label-free-t-cell-activation-monitoring-fulltechnote/) - Radiance® Label-Free T-Cell Activation MonitoringDownload The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [Radiance® Rapid Viral Quantification of Adenovirus Infection of HEK293 Cells with Label-Free Laser Force Cytology™](https://lumacyte.com/resources/tech-notes/radiance-rapid-viral-quantification-of-adenovirus-infection-of-hek293-cells-with-label-free-laser-force-cytology-fulltechnote/) - Radiance® Rapid Viral Quantification of Adenovirus Infection of HEK293 Cells with Label-Free Laser Force Cytology™Download The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [Request a Meeting](https://lumacyte.com/request-a-meeting/) - Request A Meeting Schedule a Meeting With One Of Our Experts Learn more about LumaCyte’s transformative Laser Force Cytology™ technology? How can we support your efforts in driving speed and analytical precision into your process development and manufacturing workflows. Just fill out the form below and one of our technical experts will get back to - [Fluids & Accessories](https://lumacyte.com/fluidbox-page/) - Fluids & Accessories Fluids & Accessories Thank you for contacting LumaCyte about fluids and accessories. Download the LumaCyte Safety Data Sheet. You can email sales@lumacyte.com or call (888) 472-9295 to place an order. Alternatively, please fill out the form below and an itemized list with prices or a quote will be sent you via email. Please - [MSC Differentiation Using Laser Force Cytology™](https://lumacyte.com/resources/tech-notes/msc-differentiation-using-laser-force-cytology/) - Real-Time Monitoring of Mesenchymal Stem Cell (MSC) Differentiation Using Label-Free Laser Force Cytology™Download The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [Join Our Mailing List](https://lumacyte.com/mailing-list/) - Mailing List Join Our Mailing List At LumaCyte, we are passionate about transforming the status quo. Join the LumaCyte mailing list for exclusive access to information on our new products, transformative application research, and upcoming news and events. Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to complete - [Radiance® Label-Free Monitoring of AAV Transfection in HEK293 Cells Using Laser Force Cytology™ (LFC™)](https://lumacyte.com/resources/tech-notes/radiance-label-free-monitoring-of-aav-transfection-in-hek293-cells-using-laser-force-cytology-lfc-fulltechnote/) - Radiance® Label-Free Monitoring of AAV Transfection in HEK293 Cells Using Laser Force Cytology™ (LFC™)Download The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [Laser Force Cytology™ Monitoring of Influenza Virus Infection](https://lumacyte.com/resources/tech-notes/laser-force-cytology-monitoring-of-influenza-virus-infection-fulltechnote/) - Laser Force Cytology™ Monitoring of Influenza Virus InfectionDownload The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [Zika Virus Neutralization Using Laser Force Cytology™](https://lumacyte.com/resources/tech-notes/zika-virus-neutralization-using-laser-force-cytology-fulltechnote/) - Zika Virus Neutralization Using Laser Force Cytology™Download The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [Real-time Infectivity Monitoring for Measles Vaccine Production](https://lumacyte.com/resources/tech-notes/real-time-infectivity-monitoring-for-measles-vaccine-production-fulltechnote/) - Real-time Infectivity Monitoring for Measles Vaccine ProductionDownload The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [Radiance® Rapid Label-Free Monitoring of Coronavirus Infectivity](https://lumacyte.com/resources/tech-notes/radiance-rapid-label-free-monitoring-of-coronavirus-infectivity-fulltechnote/) - Radiance® Rapid Label-Free Monitoring of Coronavirus InfectivityDownload The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [AAV2 Transduction Analytics with Laser Force Cytology™](https://lumacyte.com/resources/tech-notes/aav2-transduction-analytics-with-laser-force-cytology-fulltechnote/) - AAV2 Transduction Analytics Using Laser Force Cytology™Download The Technote How will you Harness the Power of Laser Force Cytology™ to Accelerate the Development and Production of Life Saving Therapies Faster than Ever Before?Speak To An Expert - [Scientist Course](https://lumacyte.com/academy/scientist-course/) - LFC Scientist Course Request Login Credentials to LumaCyte's LFC Scientist Course Please enable JavaScript in your browser to complete this form.Please enable JavaScript in your browser to complete this form.Name *FirstLastEmail *Phone NumberCompany or InstitutionDropdownIndividualDepartmentWhat do you hope to learn from LumaCyte's LFC Scientist Course? Submit - [Oncolytic Virus Poster](https://lumacyte.com/resources/posters/oncolytic-virus-poster/) - Monitoring the Oncolytic Effect of Talimogene Iaherparepvec (T-VEC) in Combination with the MEK Inhibitor Trametinib Using Laser Force Cytology™ The ability to rapidly and accurately determine the viral infectivity and oncolytic effects of drug candidates could help improve the speed of oncolytic vaccine R&D, product development, manufacturing, and efficacy monitoring. Here we present the results - [Vesicular Stomatitus Virus Quantification](https://lumacyte.com/resources/posters/vesicular-stomatitus-virus-quantification/) - Rapid Quantification of Vesicular Stomatitus Virus Infectivity in Vero Cells Using Laser Force Cytology™ The ability to rapidly and accurately determine viral infectivity can help improve the speed of vaccine product development and manufacturing. Current methods to determine infectious viral titers, such as the end-point dilution (50% tissue culture infective dose, TCID50) and plaque assays - [Rapid In-Process Measurement of Live Virus Vaccine Potency Using Laser Force Cytology: Paving the Way for Rapid Vaccine Development](https://lumacyte.com/resources/read-the-publications/rapid-in-process-measurement-of-live-virus-vaccine-potency-using-laser-force-cytology-paving-the-way-for-rapid-vaccine-development/) - Rapid In-Process Measurement of Live Virus Vaccine Potency Using Laser Force Cytology: Paving the Way for Rapid Vaccine Development Rapid In-Process Measurement of Live Virus Vaccine Potency Using Laser Force Cytology: Paving the Way for Rapid Vaccine Development Click The PDF To Read It Speak with one of our Laser Force Cytology experts to learn - [Footer demo](https://lumacyte.com/footer/) - Home Corporate Technology Products Solutions Services Press & Media Publications Careers Support The CyteBlog Contact Terms & Conditions Privacy Policy Schedule a Demo © 2026 LumaCyte, Inc. 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